ContactBiomedical Research Center
251 Bayview Boulevard
Baltimore, MD 21224
Fellow - General Internal Medicine - The Johns Hopkins University School of Medicine
Resident - Internal Medicine - Yale University
MD - Medicine - Boston University School of Medicine
MSc - Tropical Public Health - Harvard School of Public Health
BA - Latin American Studies and Womens Studies - The Johns Hopkins University
The Office of the Clinical Director (OCD) coordinates, supports, and supervises the development, implementation and conduct of intramural clinical research activities. The OCD provides the infrastructure needed to promote top quality clinical research and to ensure research participant safety and confidentiality. This infrastructure includes a research participant recruitment and screening center, a 45-slot addiction treatment outpatient research clinic and multiple specialized study rooms (including smoking chambers, mock MRI scanner, and physiological monitoring). In addition, a digital medical record system on a secure network has been developed and allows for all research related data to be accessible from within the IRP.
The OCD provides clinical support personnel to complement research personnel in specific laboratory groups. The personnel include clinical research nurses, research associates, mid-level providers, research pharmacists, IRB administrators, and a quality assurance medical officer.
The clinical research portfolio at the NIDA IRP includes a wide variety of collaborative investigation that focus on:
- Efficacy and safety of new treatments for drug abuse.
- Factors that impact drug taking and relapse.
- Application of MRI-based structural and functional imaging to elucidate acute and chronic drug effects and their consequences on cognitive processes.
- Specific individual genetic polymorphisms and the group variance imaging endophenotypes to understand trait related predisposition and treatment outcome.
- Molecular genetic bases of individual differences in vulnerability to develop dependence on an addictive substance.
- Recruitment and characterization of subjects for genome wide association studies.
- Development of advanced functional and structural magnetic resonance imaging/spectroscopy techniques.
- Structural MRI techniques to assess tissue integrity related to brain dysfunction.
- Transcranial magnetic Stimulation (TMS) in the elucidation and treatment of addictive disorders.
- Mobile health applications for real-time in-the-field addiction treatment interventions.