Hot Off the Press – November 21, 2022 Summary Relapse to reward seeking progressively increases during abstinence, a behavioral phenomenon termed incubation of craving. Mechanistic studies of incubation can lead to novel relapse treatments. However, previous studies have primarily used rat models and targeted region-by-region analyses, and a brain-wide functional atlas of incubation of reward… [Read More]
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Yavin Shaham Wins the 2022 Ruth L. Kirschstein Mentoring Award
Yavin Shaham, Ph.D., Chief of Behavioral Neuroscience Research Branch and Neurobiology of Relapse Section has been awarded the 2022 Ruth L. Kirschstein mentoring award by the National Institutes of Health (NIH) as part of the 2022 NIH Director’s Awards. The NIH Director’s Awards recognizes exceptional performance and special efforts beyond regular job assignments. The Ruth… [Read More]
Technology Development Initiative – Paper of the Month – November 2022
Transgenic mice for in vivo epigenome editing with CRISPR-based systems Published in Nature Methods. Authors Matthew P. Gemberling, Keith Siklenka, Erica Rodriguez, Katherine R. Tonn-Eisinger, Alejandro Barrera, Fang Liu, Ariel Kantor, Liqing Li, Valentina Cigliola, Mariah F. Hazlett, Courtney A. Williams, Luke C. Bartelt, Victoria J. Madigan, Josephine C. Bodle, Heather Daniels, Douglas C. Rouse,… [Read More]
Misconfigured striatal connectivity profiles in smokers
Featured Paper of the Month – October 2022 Published in Neuropsychopharmacology by Thomas Ross and Elliot Stein of the NIDA IRP Neuroimaging Research Branch. Summary The striatum, part of the forebrain, is critically involved in reward processes and substance use. Many of the inputs to the striatum come from frontal brain regions. One way to… [Read More]
John Hubbard awarded 2022 Humanitarian & Service PA of the Year Award
John Hubbard, MPAS, PA-C in the NIDA IRP OCD, has been awarded the 2022 Humanitarian & Service PA of the Year Award from the Maryland Academy of Physician Assistants. The MdAPA Humanitarian & Service Award seeks to recognize a PA who has shown incredible service to the community, providing care to the most vulnerable and… [Read More]
Technology Development Initiative – Paper of the Month – October 2022
Dense functional and molecular readout of a circuit hub in sensory cortex Published in Science. Authors Cameron Condylis, Abed Ghanbari, Nikita Manjrekar, Karina Bistrong, Shenqin Yao, Zizhen Yao, Thuc Nghi Nguyen, Hongkui Zeng, Bosiljka Tasic, and Jerry L. Chen Paper presented by Dr. Atul Daiwile and selected by the NIDA TDI Paper of the Month… [Read More]
Nonsuicidal Self-Injury and Substance Use Disorders: A Shared Language of Addiction
Featured Paper of the Month – October 2022 Published in Proceedings of the Eighth Workshop on Computational Linguistics and Clinical Psychology by Salvatore Giorgi and Brenda Curtis, et al. of the NIDA IRP Technology and Translational Research Unit. Summary Nonsuicidal self-injury (NSSI), or the deliberate injuring of one’s body without intending to die, has been shown… [Read More]
Acts of appetite: neural circuits governing the appetitive, consummatory, and terminating phases of feeding
Reviews To Read – September 2022. Published in Nature Metabolism and coauthored by Ana Pamela Miranda Tapia and Yeka Aponte of the Neuronal Circuits and Behavior Section (NIDA IRP) and Ivan C. Alcantara and Michael J. Krashes of the Section on Motivational Processes Underlying Appetite (NIDDK IRP). For decades, the prevalence of obesity has surged due… [Read More]
Technology Development Initiative – Paper of the Month – September 2022
SMART: An Open-Source Extension of WholeBrain for Intact Mouse Brain Registration and Segmentation Published in eNeuro. Authors Michelle Jin, Joseph D Nguyen, Sophia J Weber, Carlos A Mejias-Aponte, Rajtarun Madangopal, Sam A Golden Paper presented by Dr. Katherine Savell and selected by the NIDA TDI Paper of the Month Committee. Background and Technological Advancement Whole-brain… [Read More]
Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search
Featured Paper of the Month – September 2022 Published in Molecular Psychiatry by Jordi Bonaventura and Michael Michaelides, et al. of the NIDA IRP Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit. Summary The use of racemic ketamine and the FDA approval of (S)-ketamine are promising developments for the treatment of depression. Nevertheless, racemic ketamine and (S)-ketamine… [Read More]
