Kenzie L. Preston, Ph.D. was given the Marian W. Fischman Lectureship Award by the College on Problems of Drug Dependence as part of their 2018 Awards for Excellence. Dr. Preston was awarded on the basis the treatment research she conducts as the Senior Investigator and Chief of the Clinical Pharmacology and Therapeutics Research Branch at… [Read More]
Selective Activation of Striatal NGF-TrkA/p75NTR/ MAPK Intracellular Signaling in Rats That Show Suppression of Methamphetamine Intake 30 Days following Drug Abstinence
Featured Paper of the Month – September 2018. Methamphetamine addiction is a public health threat throughout the world. Investigators in Dr. Cadet’s laboratory in the intramural program have developed a rat model of methamphetamine addiction that includes one of the psychiatric criteria used to make that diagnosis in humans. In that model, they used footshocks… [Read More]
Cannabinoid disruption of learning mechanisms involved in reward processing
Reviews To Read – August 28, 2018. The increasing use of marijuana, its derivatives, and synthetic cannabinoids for medicinal and recreational purposes has increased interest in understanding the addictive potential of this class of molecules. Studies show that nearly 1 in 10 marijuana users will eventually show signs of dependence on the drug, which is… [Read More]
Role of Anterior Intralaminar Nuclei of Thalamus Projections to Dorsomedial Striatum in Incubation of Methamphetamine Craving.
Featured Paper of the Month – August 2018. Methamphetamine seeking progressively increases after withdrawal from drug self-administration, a phenomenon termed incubation of methamphetamine craving. We previously found that D1R-mediated dopamine transmission in dorsomedial striatum plays a critical role in this incubation phenomenon. Here, we used neuroanatomical and neuropharmacological methods in rats to demonstrate that an… [Read More]
Orbitofrontal neurons signal sensory associations underlying model-based inference in a sensory preconditioning task.
Featured Paper of the Month – July 2018. Using knowledge of the structure of the world to infer value is at the heart of model-based reasoning and relies on a circuit that includes the orbitofrontal cortex (OFC). Some accounts link this to the representation of biological significance or value by neurons in OFC, while other models focus on the representation of… [Read More]
Context-induced relapse after extinction versus punishment: similarities and differences.
Reviews To Read – June 14, 2018. This review, which is part of a special issue of Psychopharmacology on “Extinction” summarizes recent research on similarities and differences in the neuronal mechanisms of context-induced relapse after extinction-imposed abstinence (the classical model) versus context-induced relapse after punishment-imposed abstinence (the new model).
Navigating Your Life Without Losing Yourself
Tuesday June 19, 2018 • 2 – 3 pm in the BRC Atrium Panel discussion on mental health in college & career Topics will include: Self-identity Managing recovery Managing stress and workload Warning signs Seeking support and help Mentoring students Supporting marginalized students Advocating for yourself Bring your questions for the panelists or submit anonymously via… [Read More]
Delta Rhythm Orchestrates the Neural Activity Underlying the Resting State BOLD Signal via Phase–amplitude Coupling.
Featured Paper of the Month – June 2018. Our brains always work, consciously or unconsciously. Functional connectivity MRI has identified so-called resting state brain networks (e.g. default mode network). Aberrant activity in such networks is implicated in neurological and psychiatric disorders. This work applies simultaneous electrophysiological recording and functional MRI to investigate the neurophysiological basis… [Read More]
The Coffeehouse: Art of Recovery
The NIDA Eliminating Stigma Team held its first coffeehouse event on Thursday May 10th, titled “The Coffeehouse: Art of Recovery.” The audience experienced powerful stories of struggle and triumph over mental illness and drug addiction through performances and presentations of poetry, spoken word, visual art, photography, and music. The event turned the atrium into a… [Read More]
The Coffeehouse: Art of Recovery
Join the NIDA IRP for an Eliminating Stigma Series event. Experience stories of struggle and triumph over addiction and mental illness through spoken word, art, and music. Coffee and light refreshments will be served. May 10, 1:00 pm – 2:30 pm in the Biomedical Research Center Atrium.
