IRP News

Rajtarun Madangopal and Marco Venniro Awarded Brain & Behavior Research Foundation Young Investigator NARSAD Grants

The Brain & Behavior Research Foundation has awarded 2020 Young Investigator Grants to NIDA IRP staff members Rajtarun Madangopal and Marco Venniro. BBRF Young Investigator Grants provide each scientist with up to $35,000 per year for two years totaling $70,000 to enable promising investigators to either extend research fellowship training or begin careers as independent… [Read More]

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Hot Off the Press

New Challenges in Addiction Medicine: COVID-19 Infection in Patients With Alcohol and Substance Use Disorders-The Perfect Storm

Hot Off the Press – July 14 , 2020. In this article the authors discuss the heightened risks for individuals living with alcohol and substance use disorders during the current COVID-19 pandemic. Physiological, psychological, medical and economic consequences are described in relation to inaction including the far-reaching implications on the individual, society and global sphere…. [Read More]

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Reviews To Read

Advances in the science and treatment of alcohol use disorder.

Reviews To Read – March 2020. In this review, the authors critically report the scientific and clinical evidence supporting alcohol use disorder as a treatable disease using medications and/or behavioral treatments. Approved treatments and promising new interventions are reviewed and discussed, with a special emphasis on personal treatment approaches. The authors also note the critical… [Read More]

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Featured Papers

The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter

Featured Paper of the Month – September 2020. The serotonin transporter (SERT) terminates serotonin signaling by rapid presynaptic reuptake. SERT activity is modulated by antidepressants, e.g., S-citalopram and imipramine, to alleviate symptoms of depression and anxiety. SERT crystal structures reveal two S-citalopram binding pockets in the central binding (S1) site and the extracellular vestibule (S2… [Read More]

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