Molecular Neuropsychiatry Research Branch - The Intramural Research Program of the National Institute on Drug Abuse

Skip Navigation

MOLECULAR Neuropsychiatry RESEARCH BRANCH

Branch Overview

Branch Chief: Jean Lud Cadet, M.D. on-site page link

The Molecular Neuropsychiatry Research Branch is comprised of two sections: The Molecular Neuropsychiatry Section and the Neural Protection and Regeneration Section.

The Branch investigates cellular and molecular mechanisms of neurodegeneration and regeneration. Studies have focused on the role of oxidative stress, ER stress, and mitochondrial pathways in the pathogenesis of psychostimulant toxicity as well as in models of Parkinson’s disease and strokes. The Branch also investigates the potential role of specific agents in the treatment of these disorders. We are also investigating the role of epigenetic modifications in methamphetamine (METH) addiction.

Molecular Neuropsychiatry Section

Section Chief: Jean Lud Cadet, M.D. on-site page link

Our approaches are:

  • To identify changes in METH-induced gene expression in the rodent brain.
  • To investigate specific METH-induced cognitive dysfunctions in rodents.
  • To identify specific METH-induced epigenetic changes in the rodent brain.
  • To investigate the effects of METH preconditioning on gene expression and histone modifications in the brain.

Related Information...

Health and Human Services Logo National Institute on Drug Abuse Logo


The National Institute on Drug Abuse (NIDA), is part of the National Institutes of Health (NIH), the principal biomedical and behavioral research agency of the United States Government. NIH is a component of the U.S. Department of Health and Human Services.

PDF documents require the free Adobe Reader. Microsoft Word documents require the free Microsoft Word viewer. Microsoft PowerPoint documents require the free Microsoft PowerPoint viewer. Flash content requires the free Adobe Flash Player.