Post-doctoral IRTA Fellow, Neuronal Networks Section
ContactBiomedical Research Center
251 Bayview Boulevard
Suite 200, Baltimore, MD 21224
Ph.D. – University of Maryland, Baltimore, Baltimore, MD (Advisor: Dr. Mary Kay Lobo)
B.A., B.S. – Appalachian State University, Boone, NC
Chase Francis has a long-standing interest in how high frequency stimulation, commonly used in deep brain stimulation, alters motivational states. His research career began at Appalachian State University where he received his B.A. and B.S. in biology and psychology, respectively, studying the effects of audiogenic seizures on emotional states in rats under the mentorship of Dr. Mark Zrull. In 2011, he continued his training at the University of Maryland, Baltimore working in the molecular neurocircuitry lab of Dr. Mary Kay Lobo. Here, he studied the role of medium spiny neuron subtypes in outcomes to social defeat stress and uncovered molecular and structural underpinnings driving alterations in medium spiny neuron neurophysiology. He joined the Synaptic Plasticity Section of NIDA and the lab of Dr. Antonello Bonci in 2016. His current focus is on how stimulation facilitates peptide release within Nucleus Accumbens altering local circuitry and behavioral responding to salient stimuli, with the hopes of refining stimulation protocols to promote differential peptide release. In his free time he enjoys hiking, trail running, and playing guitar.
In: Curr Opin Neurobiol, 54 , pp. 66–72, 2018, ISSN: 1873-6882 (Electronic); 0959-4388 (Linking).
In: Mol Psychiatry, 22 (11), pp. 1512–1519, 2017, ISSN: 1476-5578 (Electronic); 1359-4184 (Linking).
In: Biol Psychiatry, 77 (3), pp. 212–222, 2014, ISSN: 1873-2402 (Electronic); 0006-3223 (Linking).