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Featured paper of the Month!

A figure from this studyNovember 2017

A relationship between the aldosterone-mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans.

Mol Psychiatry. 2017 May 2.

Aoun EG, Jimenez VA, Vendruscolo LF, Walter NAR, Barbier E, Ferrulli A, Haass-Koffler CL, Darakjian P, Lee MR, Addolorato G, Heilig M, Hitzemann R, Koob GF, Grant KA, Leggio L.

You can read more about this paper on PubMed.

Pictured Right: A figure from this study

Sam Golden and Conor HeinsOctober 2017

Compulsive Addiction-like Aggressive Behavior in Mice.

Biol Psychiatry. 2017 Aug 15;82(4):239-248. doi: 10.1016/j.biopsych.2017.03.004. Epub 2017 Mar 17.

Golden SA, Heins C, Venniro M, Caprioli D, Zhang M, Epstein DH, Shaham Y.

You can read more about this paper on PubMed.

Pictured Right: Sam Golden and Conor Heins

A figure from this study.September 2017

Salience and default mode network dysregulation in chronic cocaine users predict treatment outcome

Brain. 2017 Feb 20. doi: 10.1093/brain/awx036. [Epub ahead of print]

Geng X, Hu Y, Gu H, Salmeron BJ, Adinoff B, Stein EA, Yang Y.

You can read more about this paper on PubMed.

Pictured Right: A figure from this study.

Study authors Haiying Zhang, Zheng-Xiong Xi, and Guohua Bi.August 2017

The Novel Modafinil Analog, JJC8-016, as a Potential Cocaine
Abuse Pharmacotherapeutic

Neuropsychopharmacology. 2017 Aug;42(9):1871-1883. doi: 10.1038/npp.2017.41. Epub 2017 Mar 7.

Zhang HY, Bi GH, Yang HJ, He Y, Xue G, Cao J, Tanda G, Gardner EL, Newman AH, Xi ZX.

You can read more about this paper on PubMed.

Pictured Right: Study authors Haiying Zhang, Zheng-Xiong Xi, and Guohua Bi.

Study authors Vikek Kumar and Amy Moritz.July 2017

Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D3 Receptor (D3R).

J Med Chem. 2017 Feb 23;60(4):1478-1494. doi: 10.1021/acs.jmedchem.6b01688. Epub 2017 Feb 10.

Kumar V, Moritz AE, Keck TM, Bonifazi A, Ellenberger MP, Sibley CD, Free RB, Shi L, Lane JR, Sibley DR, Newman AH.

You can read more about this paper on PubMed.

Pictured Right: Study authors Vikek Kumar and Amy Moritz.

Study authors Agustin Zapata and Eun-Kyung HwangJune 2017

Lateral Habenula Involvement in Impulsive Cocaine Seeking

Neuropsychopharmacology. 2017 Apr;42(5):1103-1112. doi: 10.1038/npp.2016.286. Epub 2016 Dec 27.

Zapata A, Hwang EK, Lupica CR.

You can read more about this paper on PubMed.

Pictured Right: Study authors Agustin Zapata and Eun-Kyung Hwang

Study authors William Rea, Ning Sheng Cai and Cesar Quiroz-MolinaMay 2017

Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area.

J Neurosci. 2017 Feb 1;37(5):1176-1186. doi: 10.1523/JNEUROSCI.2442-16.2016. Epub 2016 Dec 22.

Moreno E, Quiroz C, Rea W, Cai NS, Mallol J, Cortés A, Lluís C, Canela EI, Casadó V, Ferré S.

You can read more about this paper on PubMed.

Pictured Right: Study authors William Rea, Ning Sheng Cai and Cesar Quiroz-Molina

Study author Daniele CaprioliApril 2017

Role of Dorsomedial Striatum Neuronal Ensembles in Incubation of Methamphetamine Craving after Voluntary Abstinence

Sci Adv. 2017 Jan 11;3(1):e1601631. doi: 10.1126/sciadv.1601631. eCollection 2017.

Daniele Caprioli, Marco Venniro, Michelle Zhang, Jennifer M. Bossert, Brandon L. Warren, Bruce T. Hope, and Yavin Shaham

You can read more about this paper on PubMed.

Pictured Right: Study author Daniele Caprioli

Study author Jordi BonaventuraMarch 2017

Key role of the dopamine D4 receptor in the modulation of corticostriatal glutamatergic neurotransmission.

Sci Adv. 2017 Jan 11;3(1):e1601631. doi: 10.1126/sciadv.1601631. eCollection 2017.

Bonaventura J, Quiroz C, Cai NS, Rubinstein M, Tanda G, Ferré S.

You can read more about this paper at the website for PubMed.

Pictured Right: Study author Jordi Bonaventura

Study author Sufang LiFebruary 2017

CYP2A6 Genetic Variation Alters Striatal-Cingulate Circuits, Network Hubs, and Executive Processing in Smokers.

Biol Psychiatry. 2016 Sep 28. pii: S0006-3223(16)32824-4. 2016.09.013. [Epub ahead of print]

Li S, Yang Y, Hoffmann E, Tyndale RF, Stein EA.

You can read more about this paper at the website for PubMed.

Pictured Right: Study author Sufang Li

Jordi BonaventuraJanuary 2017

Pontomesencephalic Tegmental Afferents to VTA Non-dopamine Neurons Are Necessary for Appetitive Pavlovian Learning

Cell Rep. 2016 Sep 6;16(10):2699-710. Epub 2016 Aug 25.

Yau HJ, Wang DV, Tsou JH, Chuang YF, Chen BT, Deisseroth K, Ikemoto S, Bonci A.

You can read more about this paper at the website for PubMed.

Pictured Right: Part of a figure from this study

December 2016

Glutamate neurons are intermixed with midbrain dopamine neurons in nonhuman primates and humans

Sci Rep. 2016 Aug 1;6:30615.

David H. Root, Hui-Ling Wang, Bing Liu, David J. Barker, László Mód, Péter Szocsics, Afonso C. Silva, Zsófia Maglóczky & Marisela Morales

You can read more about this paper at the website for PubMed.

November 2016

Distinct Fos-Expressing Neuronal Ensembles in the Ventromedial Prefrontal Cortex Mediate Food Reward and Extinction Memories

JNeurosci. 22 June 2016, 36 (25) 6691-6703

Brandon L. Warren, Michael P. Mendoza, Fabio C. Cruz, Rodrigo M. Leao, Daniele Caprioli, F. Javier Rubio, Leslie R. Whitaker, Kylie B. McPherson, Jennifer M. Bossert, Yavin Shaham and Bruce T. Hope

You can read more about this paper at the website for the Journal of Neuroscience.

October's Featured Paper!

Mechanism of the Association between Na Binding and Conformations at the Intracellular Gate in Neurotransmitter: Sodium Symporters

J Biol Chem. VOL. 290, NO. 22, pp. 13992–14003, May 29, 2015

Sebastian Stolzenberg, Matthias Quick, Chunfeng Zhao, Kamil Gotfryd, George Khelashvili, Ulrik Gether, Claus J. Loland, Jonathan A. Javitch, Sergei Noskov, Harel Weinstein, and Lei Shi

You can read more about this paper at the website for PubMed.

September 2016

Midbrain dopamine neurons compute inferred and cached value prediction errors in a common framework

Elife. 2016 Mar 7;5. pii: e13665.

Brian F Sadacca, Joshua L Jones, and Geoffrey Schoenbaum

You can read more about this paper at PubMed.

August 2016

Role of Ventral Subiculum in Context-Induced Relapse to Alcohol Seeking after Punishment-Imposed Abstinence

J Neurosci. 6 March 2016, 36(11): 3281-3294

Nathan J. Marchant, Erin J. Campbell, Leslie R. Whitaker, Brandon K. Harvey, Konstantin Kaganovsky, Sweta Adhikary, Bruce T. Hope, Robert C. Heins, Thomas E. Prisinzano, Eyal Vardy, Antonello Bonci, Jennifer M. Bossert, andYavin Shaham

You can read more about this paper at the website for Journal of Neuroscience.

July 2016

Hyperactive somatostatin interneurons contribute to excitotoxicity in neurodegenerative disorders

Nat Neurosci. 2016 Apr;19(4):557-9. Epub 2016 Feb 22.

Wen Zhang, Lifeng Zhang, Bo Liang, David Schroeder, Zhong-wei Zhang, Gregory A Cox, Yun Li, & Da-Ting Lin

You can read more about this paper at the website for PubMed.

June 2016

Local Control of Extracellular Dopamine Levels in the Medial Nucleus Accumbens by a Glutamatergic Projection from the Infralimbic Cortex

J Neurosci. 2016 Jan 20;36(3):851-9

César Quiroz, Marco Orrú, William Rea, Andrés Ciudad-Roberts, Gabriel Yepes, Jonathan P. Britt, and Sergi Ferré

You can read more about this paper at the website for PubMed.

May 2016

Neural Estimates of Imagined Outcomes in Basolateral Amygdala Depend on Orbitofrontal Cortex

Neuron. 2013 Oct 16; 80(2): 10.1016

Yuji K. Takahashi, Chun Yun Chang, Federica Lucantonio, Richard Z. Haney, Benjamin A. Berg, Hau-Jie Yau, Antonello Bonci, and Geoffrey Schoenbaum

You can read more about this paper at the website for PubMed.

April 2016

The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys

Biol Psychiatry. 2015 Oct 1;78(7):452-62.

Zuzana Justinova, Leigh V. Panlilio, Maria E. Secci, Godfrey H. Redhi, Charles W. Schindler, Alan J. Cross, Ladislav Mrzljak, Amy Medd, Yavin Shaham, and Steven R. Goldberg

You can read more about this paper at the website for PubMed.

March 2016

Effect of the Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 2 AZD8529 on Incubation of Methamphetamine Craving After Prolonged Voluntary Abstinence in a Rat Model

Biol Psychiatry. 2015 Oct 1;78(7):463-73

Daniele Caprioli, Marco Venniro, Tamara Zeric, Xuan Li, Sweta Adhikary, Rajtarun Madangopal, Nathan J. Marchant, Federica Lucantonio, Geoffrey Schoenbaum, Jennifer M. Bossert, and Yavin Shaham

You can read more about this paper at the website for PubMed.

February 2016

Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area

Cell Rep. 2015 Sep 29;12(12):1997-2008

Huikun Wang, Tyler Treadway, Daniel P. Covey, Joseph F. Cheer, & Carl R. Lupica

You can read more about this paper at the website for PubMed.

January 2016

High Affinity Dopamine D3 Receptor (D3R)-Selective Antagonists Attenuate Heroin Self-Administration in Wild-Type but not D3R Knockout Mice

J Med Chem. 2015 Aug 13;58(15):6195-213.

Comfort A. Boateng, Oluyomi M. Bakare, Jia Zhan, Ashwini K. Banala, Caitlin Burzynski, Elie Pommier, Thomas M. Keck, Prashant Donthamsetti, Jonathan A. Javitch, Rana Rais, Barbara S. Slusher, Zheng-Xiong Xi, and Amy Hauck Newman

You can read more about this paper at the website for PubMed.

December 2015

SERCaMP: a carboxy Structure−Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists

J Med Chem. 2015 Jun 25;58(12):5038-52.

Brandon R. Selfridge, Xiaohui Wang, Yingning Zhang, Hang Yin, Peter M. Grace, Linda R. Watkins, Arthur E. Jacobson, and Kenner C. Rice

You can read more about this paper at the website for PubMed.

November 2015

SERCaMP: a carboxy Impaired functional connectivity within and between frontostriatal circuits and its association with compulsive drug use and trait impulsivity in cocaine addiction.

JAMA Psychiatry 2015 Jun;72(6):584-92

Hu Y, Salmeron BJ, Gu H, Stein EA, Yang Y.

You can read more about this paper at the website for PubMed.

October 2015

SERCaMP: a carboxy Mechanism of the Association between Na Binding and Conformations at the Intracellular Gate in Neurotransmitter: Sodium Symporters

J Biol Chem. VOL. 290, NO. 22, pp. 13992–14003, May 29, 2015

Sebastian Stolzenberg, Matthias Quick, Chunfeng Zhao, Kamil Gotfryd, George Khelashvili, Ulrik Gether, Claus J. Loland, Jonathan A. Javitch, Sergei Noskov, Harel Weinstein, and Lei Shi

You can read more about this paper at the website for PubMed.

September 2015

SERCaMP: a carboxy Incubation of methamphetamine craving is associated with selective increases in expression of Bdnf and Trkb, glutamate receptors, and epigenetic enzymes in cue-activated fos-expressing dorsal striatal neurons.

J Neurosci. 2015 May 27;35(21):8232-44.

Xuan Li, F. Javier Rubio, Tamara Zeric, Jennifer M. Bossert, Sarita Kambhampati, Hannah M. Cates, Pamela J. Kennedy, Qing-Rong Liu, Raffaello Cimbro, Bruce T. Hope, Eric J. Nestler, and Yavin Shaham

You can read more about this paper at the website for PubMed.

August 2015

SERCaMP: a carboxy Norepinephrine activates dopamine D4 receptors in the rat lateral habenula.

J Neurosci. 2015 Feb 25;35(8):3460-9.

David H. Root, Alexander F. Hoffman, Cameron H. Good, Shiliang Zhang, Eduardo Gigante, Carl R. Lupica, and Marisela Morales

You can read more about this paper at the website for PubMed.

July 2015

SERCaMP: a carboxy Basal Hippocampal Activity and Its Functional Connectivity Predicts Cocaine Relapse

Biol Psychiatry. 2015 Jan 30. pii: S0006-3223(15)00045-1

Bryon Adinoff, Hong Gu, Carmen Merrick, Meredith McHugh, Haekyung Jeon-Slaughter, Hanzhang Lu, Yihong Yang, and Elliot A. Stein

You can read more about this paper at the website for PubMed.

June 2015

SERCaMP: a carboxy R-Modafinil Attenuates Nicotine-Taking and Nicotine-Seeking Behavior in Alcohol-Preferring Rats

Neuropsychopharmacology 2015 Jun;40(7):1762-71

Xiao-Fei Wang, Guo-Hua Bi, Yi He, Hong-Ju Yang, Jun-Tao Gao, Oluyomi M Okunola-Bakare, Rachel D Slack, Eliot L Gardner, Zheng-Xiong Xi, and Amy Hauck Newman

You can read more about this paper at the website for PubMed.

May 2015

SERCaMP: a carboxy Central role for the insular cortex in mediating conditioned responses to anticipatory cues

PNAS January 27, 2015 vol. 112 no. 4 1190-1195

Ikue Kusumoto-Yoshida, Haixin Liu, Billy T. Chen, Alfredo Fontanini, and Antonello Bonci

You can read more about this paper at the website for PNAS.

April 2015

SERCaMP: a carboxy An in vitro model of human neocortical development using pluripotent stem cells: cocaine-induced cytoarchitectural alterations

DMM 2014 vol. 7 no. 12 1397-1405

Abigail A. Kindberg, Raphael M. Bendriem, Charles E. Spivak, Jia Chen, Annelie Handreck, Carl R. Lupica, Jinny Liu, William J. Freed, and Chun-Ting Lee

You can read more about this paper at the website for Disease Models & Mechanisms.

March 2015

SERCaMP: a carboxy Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.

Mol Pharmacol. 2014 Oct;86(4):417-29.

Xavier Guitart, Gemma Navarro, Estefania Moreno, Hideaki Yano, Ning-Sheng Cai, Marta Sánchez-Soto, Sandeep Kumar-Barodia, Yamini T. Naidu, Josefa Mallol, Antoni Cortés, Carme Lluís, Enric I. Canela, Vicent Casadó, Peter J. McCormick, and Sergi Ferré

You can read more about this paper at the website for PubMed.

February 2015

SERCaMP: a carboxy Synthesis and immunological effects of heroin vaccines

Org Biomol Chem. 2014 Oct 7;12(37):7211-32.

Li F, Cheng K, Antoline JF, Iyer MR, Matyas GR, Torres OB, Jalah R, Beck Z, Alving CR, Parrish DA, Deschamps JR, Jacobson AE, Rice KC

You can read more about this paper at the website for PubMed.

January 2015

SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis

Mol Biol Cell. 2014 Sep 15;25(18):2828-39

Mark J. Henderson, Emily S. Wires, Kathleen A. Trychta, Christopher T. Richie, and Brandon K. Harvey

You can read more about this paper at the website for PubMed.

December 2014

Intravenous ghrelin administration increases alcohol craving in alcohol-dependent heavy drinkers: a preliminary investigation.

Biol Psychiatry. 2014 Nov 1;76(9):734-41

Lorenzo Leggio, William H. Zywiak, Samuel R. Fricchione, Steven M. Edwards, Suzanne M. de la Monte, Robert M. Swift, and George A. Kenna

You can read more about this paper at the website for PubMed.

November 2014

2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter

J Pharmacol Exp Ther. 2014 May;349(2):297-309

Takato Hiranita, Derek S. Wilkinson, Weimin C. Hong, Mu-Fa Zou, Theresa A. Kopajtic, Paul L. Soto, Carl R. Lupica, Amy H. Newman, and Jonathan L. Katz

You can read more about this paper at the website for PubMed.

October 2014

Evidence for a Role of Transporter-Mediated Currents in the Depletion of Brain Serotonin Induced by Serotonin Transporter Substrates

Neuropsychopharmacology (2014) 39, 1355–1365.

Michael H Baumann, Simon Bulling, Tova S Benaderet, Kusumika Saha, Mario A Ayestas, John S Partilla, Syed F Ali, Thomas Stockner, Richard B Rothman, Walter Sandtner, and Harald H Sitte

You can read more about this paper at the website for PubMed.

September 2014

Differential Effects of Presynaptic versus Postsynaptic Adenosine A2A Receptor Blockade onΔ9-Tetrahydrocannabinol (THC) Self-Administration in Squirrel Monkeys

J Neurosci. 2014 May 7;34(19):6480-4.

Zuzana Justinova, Godfrey H. Redhi, Steven R. Goldberg, and Sergi Ferre

You can read more about this paper at the website for PubMed.

August 2014

Gangliosides and Ceramides Change in a Mouse Model of Blast Induced Traumatic Brain Injury

ACS Chem. Neurosci., 2013, 4 (4), pp 594–600

Amina S. Woods, Benoit Colsch, Shelley N. Jackson, Jeremy Post, Kathrine Baldwin, Aurelie Roux, Barry Hoffer, Brian M. Cox, Michael Hoffer, Vardit Rubovitch, Chaim G. Pick, J. Albert Schultz, and Carey Balaban.

You can read more about this paper at the website for ASC Chemical Neuroscience.

July 2014

Elucidation of Structural Elements for Selectivity across Monoamine Transporters: Novel 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues

J Med Chem 2014, 57, 1000-1013

Oluyomi M. Okunola-Bakare, Jianjing Cao, Theresa Kopajtic, Jonathan L. Katz, Claus J. Loland, Lei Shi, and Amy Hauck Newman.

You can read more about this paper at the website for PubMed.

June 2014

Similar Roles of Substantia Nigra and Ventral Tegmental Dopamine Neurons in Reward and Aversion

J Neurosci. 2014 Jan 15;34(3):817-22. doi: 10.1523/JNEUROSCI.1703-13.2014

Anton Ilango, Andrew J. Kesner, Kristine L. Keller, Garret D. Stuber, Antonello Bonci, Satoshi Ikemoto.

You can read more about this paper at the website for PubMed.

May 2014

Real-time tracking of neighborhood surroundings and mood in urban drug misusers: Application of a new method to study behavior in its geographical context

Drug and Alcohol Dependence 134 (2014) 22– 29

David H. Epstein, Matthew Tyburski, Ian M. Craig, Karran A. Phillips, Michelle L. Jobes, Massoud Vahabzadeh, Mustapha Mezghanni, Jia-Ling Lin, C. Debra M. Furr-Holden, Kenzie L. Preston

You can read more about this paper at the website for PubMed.

April 2014

Methamphetamine Downregulates Striatal Glutamate Receptors via Diverse Epigenetic Mechanisms

BIOL PSYCHIATRY, 2013.09.034

Subramaniam Jayanthi, Michael T. McCoy, Billy Chen, Jonathan P. Britt, Saïd Kourrich, Hau-Jie Yau, Bruce Ladenheim, Irina N. Krasnova, Antonello Bonci, and Jean Lud Cadet

You can read more about this paper at the website for Science Direct.

March 2014

Large-Scale Brain Networks in the Awake, Truly Resting Marmoset Monkey

The Journal of Neuroscience, 16 October 2013, 33(42): 16796-16804

Annabelle M. Belcher, Cecil C. Yen, Haley Stepp, Hong Gu, Hanbing Lu, Yihong Yang, Afonso C. Silva, and Elliot A. Stein

You can read more about this paper at the website for the Journal of Neuroscience.

February 2014

Dopamine D4 Receptor Excitation of Lateral Habenula Neurons via Multiple Cellular Mechanisms

The Journal of Neuroscience, October 23, 2013 • 33(43):16853–16864 • 16853

Cameron H. Good, Huikun Wang, Yuan-Hao Chen, Carlos A. Mejias-Aponte, Alexander F. Hoffman, and Carl R. Lupica

You can read more about this paper at the website for the Journal of Neuroscience.

January 2014

Resting-State Glutamate and GABA Concentrations Predict Task-Induced Deactivation in the Default Mode Network

J. NEUROSCI 20 November 2013, 33(47): 18566-18573

Yuzheng Hu, Xi Chen, Hong Gu, and Yihong Yang

You can read more about this paper at the website for theJournal of Neuroscience.

December 2013

Down-Regulation of Amygdala and Insula Functional Circuits by Varenicline and Nicotine in Abstinent Cigarette Smokers

BIOL PSYCH Oct 1, 2013 -74(7):538-546

Matthew T. Sutherland, Allison J. Carroll, Betty Jo Salmeron, Thomas J. Ross, L. Elliot Hong, and Elliot A. Stein

You can read more about this paper at the website for the Journal of Biological Psychiatry.

November 2013

Rapid Sensitization of Physiological, Neuronal, and Locomotor Effects of Nicotine: Critical Role of Peripheral Drug Actions

J Neurosci June 12, 2013 -33(24):9937–9949

Magalie Lenoir, Jeremy S. Tang, Amina S. Woods, and Eugene A. Kiyatkin

You can read more about this paper at the website for theJournal of Neuroscience.

October 2013

CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat

Neurobiology of Disease 58 (2013) 132–143

Irina N. Krasnova, Margarit Chiflikyan, Zuzana Justinova, Michael T. McCoy, Bruce Ladenheim, Subramaniam Jayanthi, Cynthia Quintero, Christie Brannock, Chanel Barnes, Jordan E. Adair, Elin Lehrmann, Firas H. Kobeissy, Mark S. Gold, Kevin G. Becker, Steven R. Goldberg, Jean Lud Cadet

You can read more about this paper at the website for Science Direct.

September 2013

Cocaine Drives Aversive Conditioning via Delayed Activation of Dopamine-Responsive Habenular and Midbrain Pathways

JNEUROSCI 24 April 2013, 33(17): 7501-7512

Thomas C. Jhou, Cameron H. Good, Courtney S. Rowley, Sheng-ping Xu, Huikun Wang, Nathan W. Burnham, Alexander F. Hoffman, Carl R. Lupica, and Satoshi Ikemoto

You can read more about this paper at the website for The Journal of Neuroscience.

August 2013

Effect of Chronic Delivery of the Toll-like Receptor 4 Antagonist (+)-Naltrexone on Incubation of Heroin Craving

BIOL PSYCHIATRY 2013;73:729–737

Florence R. Theberge, Xuan Li, Sarita Kambhampati, Charles L. Pickens, Robyn St. Laurent, Jennifer M. Bossert, Michael H. Baumann, Mark R. Hutchinson, Kenner C. Rice, Linda R. Watkins, and Yavin Shaham

You can read more about this paper at the website for Science Direct.

July 2013

Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Secretion and Cell Surface Binding Are Modulated by KDEL Receptors

J. BIOL. CHEM. February 8, 2013, 288, 4209-4225.

Mark J. Henderson, Christopher T. Richie, Mikko Airavaara, Yun Wang, and Brandon K. Harvey

You can read more about this paper at the website for The Journal of Biological Chemistry.

June 2013

Acute Nicotine Differentially Impacts Anticipatory Valence- and Magnitude-Related Striatal Activity

BIOL PSYCHIATRY 2013;73:280–288

Emma Jane Rose, Thomas J. Ross, Betty Jo Salmeron, Mary Lee, Diaa M. Shakleya, Marilyn A. Huestis, and Elliot A. Stein

You can read more about this paper at the website for Science Direct.

May 2013

Coupling of functional connectivity and regional cerebral blood flow reveals a physiological basis for network hubs of the human brain

PNAS January 29, 2013 vol. 110 no. 5 1929-1934

Xia Liang, Qihong Zou, Yong He, and Yihong Yang

You can read more about this paper at the website for The Proceedings of the National Academy of Sciences.

April 2013

Optogenetic Inhibition of Dorsal Medial Prefrontal Cortex Attenuates Stress-Induced Reinstatement of Palatable Food Seeking in Female Rats

JNeurosci 2 January 2013, 33(1): 214-226; doi:10.1523/JNEUROSCI.2016-12.2013

Donna J. Calu, Alex B. Kawa, Nathan J. Marchant, Brittany M. Navarre, Mark J. Henderson, Billy Chen, Hau-Jie Yau, Jennifer M. Bossert, Geoffrey Schoenbaum, Karl Deisseroth, Brandon K. Harvey, Bruce T. Hope, and Yavin Shaham

You can read more about this paper at the website for The Journal of Neuroscience.

March 2013

Mapping of reinforcing and analgesic effects of the mu opioid agonist Endomorphin-1 in the ventral midbrain of the rat

Psychopharmacology Published online before print, 6 June 2012, 224:303–312

Thomas C. Jhou & Sheng-Ping Xu & Mary R. Lee, Courtney L. Gallen, & Satoshi Ikemoto

You can read more about this paper at the website for PubMed.

February 2013

PIncreased vulnerability to cocaine in mice lacking dopamine D3 receptors

PNAS Published online before print, October 8, 2012, doi:10.1073/pnas.1205297109

Rui Songa, Hai-Ying Zhang, Xia Li, Guo-Hua Bi, Eliot L. Gardner, and Zheng-Xiong Xi

You can read more about this paper at the website for PNAS.

January 2013

Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products

Neuropsychopharmacology advance online publication, 17 October 2012; doi:10.1038/npp.2012.204

Michael H Baumann, John S Partilla, Kurt R Lehner, Eric B Thorndike Alexander F Hoffman, Marion Holy, Richard B Rothman, Steven R Goldberg, Carl R Lupica, Harald H Sitte, Simon D Brandt, Srihari R Tella, Nicholas V Cozzi, Charles W Schindler

You can read more about this paper at the website for Neuropsychopharmacology.

December 2012

R-Modafinil (Armodafinil): A Unique Dopamine Uptake Inhibitor and Potential Medication for Psychostimulant Abuse

Biol. Psych., 2012;72:405–413

Claus J. Loland, Maddalena Mereu, Oluyomi M. Okunola, Jianjing Cao, Thomas E. Prisinzano, Sonia Mazier, Theresa Kopajtic, Lei Shi, Jonathan L. Katz, Gianluigi Tanda, Amy Hauck Newman

You can read more about this paper at the website for Science Direct.

November 2012

Antagonism of Sigma-1 Receptors Blocks Compulsive-Like Eating

Neuropsychopharmacology, 2012 Nov;37(12):2593-604. doi: 10.1038/npp.2012.89

Pietro Cottone, Xiaofan Wang, Jin Won Park, Marta Valenza, Angelo Blasio, Jina Kwak, Malliga R Iyer, Luca Steardo, Kenner C Rice, Teruo Hayashi, and Valentina Sabino

You can read more about this paper at the website for Neuropsychopharmacology.

October 2012

Molecular Determinants of Selectivity and Efficacy at the Dopamine D3 Receptor

J. Med. Chem., 2012, 55 (15), pp 6689–6699 | DOI: 10.1021/jm300482h

Amy Hauck Newman, Thijs Beuming, Ashwini K. Banala, Prashant Donthamsetti, Katherine Pongetti, Alex LaBounty, Benjamin Levy, Jianjing Cao, Mayako Michino, Robert R. Luedtke, Jonathan A. Javitch, and Lei Shi

You can read more about this paper at the website for the Journal of Medicinal Chemistry.

September 2012

Medial Prefrontal Cortex Neuronal Activation and Synaptic Alterations after Stress-Induced Reinstatement of Palatable Food Seeking: A Study Using c-fos-GFP Transgenic Female Rats

J. Neurosci, June 20, 2012 • 32(25):8480–8490

Carlo Cifani, Eisuke Koya, Brittany M. Navarre, Donna J. Calu, Michael H. Baumann, Nathan J. Marchant, Qing-Rong Liu, Thi Khuc, James Pickel, Carl R. Lupica, Yavin Shaham, and Bruce T. Hope

You can read more about this paper at the website for the Journal of Neuroscience.

August 2012

Methamphetamine Causes Differential Alterations in Gene Expression and Patterns of Histone Acetylation/ Hypoacetylation in the Rat Nucleus Accumbens

PLoS ONE 7(3): e34236. doi:10.1371/journal.pone.0034236

Tracey A. Martin, Subramaniam Jayanthi, Michael T. McCoy, Christie Brannock, Bruce Ladenheim, Tiffany Garrett, Elin Lehrmann, Kevin G. Becker, Jean Lud Cadet

You can read more about this paper at the website for the The Public Library of Science.

July 2012

Role of Projections from Ventral Medial Prefrontal Cortex to Nucleus Accumbens Shell in Context-Induced Reinstatement of Heroin Seeking

J. Neurosci April 4, 2012 | 32(14):4982– 4991

Jennifer M. Bossert, Anna L. Stern, Florence R. M. Theberge, Nathan J. Marchant, Hui-Ling Wang, Marisela Morales, and Yavin Shaham

You can read more about this paper at the website for the The Journal of Neuroscience.

June 2012

Novel Use of a Lipid-Lowering Fibrate Medication to Prevent Nicotine Reward and Relapse: Preclinical Findings

Neuropsychopharmacology advance online publication, 28 March 2012; doi:10.1038/npp.2012.31

Leigh V Panlilio, Zuzana Justinova, Paola Mascia, Marco Pistis, Antonio Luchicchi, Salvatore Lecca, Chanel Barnes, Godfrey H Redhi, Jordan Adair, Stephen J Heishman, Sevil Yasar, Mano Aliczki, Jozsef Haller, and Steven R Goldberg

You can read more about this paper at the website for the Neuropsychopharmacology.

May 2012

Expectancy-related changes in firing of dopamine neurons depend on orbitofrontal cortex

Nature Neuroscience 14, 1590–1597 (2011) doi:10.1038/nn.2957 Received 14 July 2011 | Accepted 15 September 2011 | Published online 30 October 2011

Yuji K Takahashi, Matthew R Roesch, Robert C Wilson, Kathy Toreson, Patricio O’Donnell, Yael Niv & Geoffrey Schoenbaum

You can read more about this paper at the website for the Nature Neuroscience.

April 2012

Rat brains also have a default mode network

PNAS March 6, 2012 vol. 109 no. 10 3979-3984 | doi:10.1073/pnas.1200506109

Hanbing Lu, Qihong Zou, Hong Gu, Marcus E. Raichle, Elliot A. Stein, and Yihong Yang

You can read more about this paper at the website for the Proceedings for the National Academy of Sciences.

March 2012

Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors

JPET November 2011 vol. 339 no. 2 662-677 | doi:10.1124/jpet.111.185025

Takato Hiranita, Paul L. Soto, Stephen J. Kohut, Theresa Kopajtic, Jianjing Cao, Amy H. Newman, Gianluigi Tanda, and Jonathan L. Katz

You can read more about this paper at the website for Journal of Pharmacology and Experimental Therapeutics.

February's 2012

Basolateral Amygdala-Driven Augmentation of Medial Prefrontal Cortex GABAergic Neurotransmission in Response to Environmental Stimuli Associated with Cocaine Administration

Neuropsychopharmacology 1 June 2011; 36, 2018 2029; doi:10.1038/npp.2011.89

Vladimir I Chefer, Ruizhong Wang, and Toni S Shippenberg

You can read more about this paper at the website for Neuropsychophamacology.

January 2012

The Designer Methcathinone Analogs, Mephedrone and Methylone, are Substrates for Monoamine Transporters in Brain Tissue

Neuropsychopharmacology 14 December 2011; doi: 10.1038/npp.2011.304

Michael H Baumann, Mario A Ayestas Jr, John S Partilla, Jacqueline R Sink, Alexander T Shulgin, Paul F Daley, Simon D Brandt, Richard B Rothman, Arnold E Ruoho, and Nicholas V Cozzi

You can read more about this paper at the website for Neuropsychophamacology.

 

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