Featured Paper of the Month – December 2017. The etiology and pathophysiology of drug addiction are still not well understood. In this research paper, we show that genetic deletion of mGluR2, a presynaptic glutamate autoreceptor, decreases sensitivity to cocaine reward that causes a compensatory increase in cocaine intake and a decrease in relapse to cocaine-seeking… [Read More]
Featured Paper of the Month
A relationship between the aldosterone-mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans.
Featured Paper of the Month – November 2017
This paper describes three separate studies, conducted with non-human primates, rats, and humans, that investigated the potential contribution of the hormone aldosterone and its mineralocorticoid receptor to alcohol use disorder.
Compulsive Addiction-like Aggressive Behavior in Mice.
Featured Paper of the Month – October 2017
Golden, Sam A; Heins, Conor; Venniro, Marco; Caprioli, Daniele; Zhang, Michelle; Epstein, David H; Shaham, Yavin
Biol Psychiatry, 82 (4), pp. 239–248, 2017, ISSN: 1873-2402 (Electronic); 0006-3223 (Linking)
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Salience and default mode network dysregulation in chronic cocaine users predict treatment outcome.
Featured Paper of the Month – September 2017
Geng, Xiujuan; Hu, Yuzheng; Gu, Hong; Salmeron, Betty Jo; Adinoff, Bryon; Stein, Elliot A; Yang, Yihong
Brain, 140 (5), pp. 1513–1524, 2017, ISSN: 1460-2156 (Electronic); 0006-8950 (Linking).
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The Novel Modafinil Analog, JJC8-016, as a Potential Cocaine Abuse Pharmacotherapeutic.
Featured Paper of the Month – August 2017
Zhang, Hai-Ying; Bi, Guo-Hua; Yang, Hong-Ju; He, Yi; Xue, Gilbert; Cao, Jiajing; Tanda, Gianluigi; Gardner, Eliot L; Newman, Amy Hauck; Xi, Zheng-Xiong
Neuropsychopharmacology, 42 (9), pp. 1871–1883, 2017, ISSN: 1740-634X (Electronic); 0893-133X (Linking).
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Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D3 Receptor (D3R).
Featured Paper of the Month – July 2017
Kumar, Vivek; Moritz, Amy E; Keck, Thomas M; Bonifazi, Alessandro; Ellenberger, Michael P; Sibley, Christopher D; Free, Benjamin R; Shi, Lei; Lane, Robert J; Sibley, David R; Newman, Amy Hauck
J Med Chem, 60 (4), pp. 1478–1494, 2017, ISSN: 1520-4804 (Electronic); 0022-2623 (Linking).
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Lateral Habenula Involvement in Impulsive Cocaine Seeking
Featured Paper of the Month – June 2017
Zapata, Agustin; Hwang, Eun-Kyung; Lupica, Carl R
Neuropsychopharmacology, 42 (5), pp. 1103–1112, 2016, ISSN: 1740-634X (Electronic); 0893-133X (Linking).
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Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area.
Featured Paper of the Month – May 2017
Estefania Moreno, Cesar Quiroz, William Rea, Ning-Sheng Cai, Josefa Mallol, Antoni Cortes, Carme Lluis, Enric I Canela, Vicent Casado, Sergi Ferré
J Neurosci, 37 (5), pp. 1176–1186, 2017, ISSN: 1529-2401 (Electronic); 0270-6474 (Linking).
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Role of Dorsomedial Striatum Neuronal Ensembles in Incubation of Methamphetamine Craving after Voluntary Abstinence
Featured Paper of the Month – April 2017
Caprioli, Daniele; Venniro, Marco; Zhang, Michelle; Bossert, Jennifer M; Warren, Brandon L; Hope, Bruce T; Shaham, Yavin
J Neurosci, 37 (4), pp. 1014–1027, 2017, ISSN: 1529-2401 (Electronic); 0270-6474 (Linking).
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Key role of the dopamine D4 receptor in the modulation of corticostriatal glutamatergic neurotransmission.
Featured Paper of the Month – March 2017
Bonaventura, Jordi; Quiroz, Cesar; Cai, Ning-Sheng; Rubinstein, Marcelo; Tanda, Gianluigi; Ferre, Sergi
Sci Adv, 3 (1), pp. e1601631, 2017, ISSN: 2375-2548 (Electronic); 2375-2548 (Linking).
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