Amy Hauck Newman, Ph.D., Senior Investigator - Principal Investigators - The Intramural Research Program of the National Institute on Drug Abuse

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Amy Hauck Newman, Ph.D., Senior Investigator


Triad Technology Center
333 Cassell Drive
Rm 3444
Baltimore, MD 21224

Phone: 443-740-2887
Fax: 443-740-2111

Amy Hauck Newman, Ph.D., Deputy Scientific Director

Chief, Molecular Targets and Medications Discovery Branch
Chief, Medicinal Chemistry Section
Director, Medication Development Program

Post-doctoral Training - Laboratory of Medicinal Chemistry, NIDDK, NIH (advisor: Dr. Kenner C. Rice)

Ph. D. - Medicinal Chemistry, Medical College of Virginia, Virginia Commonwealth University (thesis advisor: Dr. Richard Glennon)

B.S. - Chemistry, Mary Washington College


Our research effort is focused on the design and synthesis of novel ligands to study the function of selected G-protein coupled receptors and monoamine transporters in the central nervous system. Highly selective compounds are designed and synthesized for characterization of these molecular targets and to develop structure-activity relationships. In addition, specific tools such as fluorescent and radiolabeled ligands are synthesized for receptor or transporter structure-function studies. My research program is currently studying the dopamine and serotonin transport systems and the dopamine D2 receptor family (D2/D3) through the design, synthesis and pharmacological evaluation of novel ligands. The combination of state of the art synthetic organic chemistry techniques with molecular modeling and interpretation of pharmacological data has resulted in the discovery of important molecular probes for studying these neurochemical targets. It is envisioned that, ultimately, this multidisciplinary approach will provide new leads toward the development of potential pharmacotherapeutic agents for the treatment of addiction.

Selected Publications:

  • View more publications at PubMed.

More about Dr. Newman

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The National Institute on Drug Abuse (NIDA), is part of the National Institutes of Health (NIH), the principal biomedical and behavioral research agency of the United States Government. NIH is a component of the U.S. Department of Health and Human Services.

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