People at the NRB
photo of  Jennifer A. Stark, Ph.D
Jennifer A. Stark, Ph.D

Visiting Fellow | Starkja@mail.nih.gov

Jennifer graduated from the University of Wales, Cardiff in 2002 with an honors degree in Neuroscience. This included a year in industry where she took a 9 month position at the Mario Negri Institute in Milan, Italy, investigating reinstatement of cocaine-seeking behavior in rats. Since then, she has completed a Ph.D in neuroscience from the University of Manchester, UK, in 2006, which involved developing in vivo magnetic resonance imaging to study appetite systems in the rat. During the following 3 year post doctoral position in the same laboratory she investigated the role of ghrelin in appetite and reward systems in rats using MRI and histological techniques. Jennifer began her position at the Neuroimaging Research Branch at NIDA in October 2009 to develop her research interests in drug abuse and reward systems using MRI.

Projects:

  • Jennifer is currently developing a project that involves imaging brain networks in conscious rats, implicated in craving leading to reinstatement of drug-seeking behavior.

Publications:

  • Dodd, GT*, Stark, JA*, Mckie, S, Williams, SR, Luckman, SM. Central cannabinoid signalling in the rat: pharmacological challenge MRI and functional histology study. Neuroscience 2009, 163(4), 1192 – 1200.
  • Stark, JA, McKie, S, Davies, KE, Williams, SR, Luckman SM. 5-HT2C antagonism blocks blood oxygen level-dependent pharmacological-challenge magnetic resonance imaging signal in rat brain areas related to feeding. European Journal of Neuroscience 2008, 27: 457 – 465.
  • Stark, JA, Davies, KE, Williams SR, Luckman SM. Functional magnetic resonance imaging and c-Fos mapping in rats following an anorectic dose of m-chlorophenylpiperazine. Neuroimage 2006, 31: 1228 – 1237.
  • Scott, V, Kimura, N, Stark, JA, Luckman SM. Intravenous peptide YY3-36 and Y2 receptor antagonism in the rat: effects on feeding behaviour. Journal of Neuroendocrinology 2005, 17: 452 – 457.
  • Campiani, G, Butini, S, Trotta, F, Fattorusso, C, Catalanotti, B, Aiello, F, Gemma, S, Nacci, V, Novellino, E, Stark, JA, Cagnotto, A, Fumagalli, E, Carnovali, F, Cervo, L, Mennini, T. Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: Inhibition of cocaine-seeking behaviour and the role of dopamine D3/D2 receptors. Journal of Medicinal Chemistry 2003, 46: 3822 – 3839.
  • Cervo, L, Carnovali, F, Stark, JA, Mennini T. Cocaine-seeking behaviour in response to drug-associated stimuli in rats: are D3 dopamine receptors involved? Neuropsychopharmacology 2003, 28:1150 – 1159.
 
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